Any of you dudes remember playing pokemon as kids? Basic medical supplies like elixirs were just not sold in any stores; you had to find them in dungeons and old ruins. This suggests that they used to be produced, but aren't anymore. Maybe there was a horrible, apocalyptic economic collapse, and all the factories closed? It'd explain a lot, now that I think about it. Silph co is the only major economic power aside from the mob, and there are rows upon rows of buildings with no people in them and no doors. Perhaps most of the people starved and they just sealed up the entrances?